Thrombosis Of The Vena Cava

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TheCattleSite: Diseases and Conditions

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Although this is generally a rare condition, it is important to recognise it as it is usually caused by a much more common condition, liver abscess. Thus for every animal with thrombosis of the vena cava, there will be many more with significant liver damage due to abscesses

The development of Thrombosis

Most cases of thrombosis occur as a result of an abscess forming in the liver. The infection spreads from the liver to cause a localised infection in the vein that passes near the liver, the vena cava. The localised infection can then result in the development of a solid mass (a thrombus) in the vena cava. The thrombus is made up of made up of clotted blood, dead white blood cells, bacteria and other cells. Once formed, these thrombi can detach from the lining of the vena cava (they are then called emboli) and are carried in the bloodstream through to smaller blood vessels, where they become stuck. The most common site is in the lungs. Emboli in the lungs result in chronic pneumonia and the development of multiple lung abscesses

Clinical Signs

Sudden death - usually the animal is found dead with a pool of blood in front of it

B) Acute disease
Cattle can show respiratory disease for a variable period (from a few days to several months) prior to the development of other signs.
Affected cattle will cough up blood, with frothy blood often seen around nose and mouth
Chest pain and difficulty breathing common
Black, tarry faeces common
Weakening, collapse and death (usually within seven days of beginning to cough up blood)
In some animals, heart failure will occur

Diagnosis

On the clinical signs described above
Finding liver abscesses and clots in the vena cava at post mortem

Treatment

No effective treatment
Casualty slaughter affected animals if they are not severely ill may be the only option

Prevention

Prevent liver abscesses. Liver abscesses occur primarily as a result of acidosis.
To prevent acidosis:
a)Make sure that all changes in feeding are undertaken as slowly as possible

b)Maximise forage intake
Treat all abscesses, wherever found, adequately to minimise the risk of spread.

NADIS (National Animal Disease Information Service) is a network of 40 veterinary practices and 6 veterinary colleges monitoring diseases in cattle, sheep and pigs in the UK, including BPEX, EBLEX, HCC, QMS, Elanco Animal Health, MLC and Merial

TheCattleSite: Diseases and Conditions